Recombinant cow FGF2 Protein
Beta LifeScience
SKU/CAT #: BLA-1791P
Recombinant cow FGF2 Protein
Beta LifeScience
SKU/CAT #: BLA-1791P
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Host Species | Cow |
Accession | P03969 |
Synonym | Basic fibroblast growth factor Basic fibroblast growth factor bFGF BFGF FGF 2 FGF B FGF-2 Fgf2 FGF2 basic FGF2_HUMAN FGFB Fibroblast growth factor 2 Fibroblast growth factor 2 (basic) Fibroblast growth factor, basic HBGF 2 HBGF-2 HBGF2 HBGH 2 HBGH2 Heparin binding growth factor 2 precursor Heparin-binding growth factor 2 Prostatropin |
Description | Recombinant cow FGF2 Protein was expressed in E.coli. It is a Full length protein |
Source | E.coli |
AA Sequence | The sequence of the first five N-terminal amino acids was determined and was found to be Met-Ala-Ala-Gly-Ser. |
Molecular Weight | 17 kDa |
Purity | Greater than = 97% SDS-PAGE |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method |
Bioactivity | The ED50, measured in a mitogenic assay using quiescent NR6R-3T3 fibroblasts was found to be <0.1 ng/ml, corresponding to a specific activity of 10 MUnits/mg. |
Formulation | Lyophilised |
Stability | The recombinant protein samples are stable for up to 12 months at -80°C |
Reconstitution | See related COA |
Unit Definition | For Research Use Only |
Storage Buffer | Shipped at 4°C. Store at -20°C. |
Target Details
Target Function | Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation. |
Subcellular Location | Secreted. Nucleus. |
Protein Families | Heparin-binding growth factors family |
Database References | STRING: 9913.ENSBTAP00000007477 UniGene: Bt.66957 |