Recombinant Human PKC iota Protein
Beta LifeScience
SKU/CAT #: BLK-00183P-100UG
Human PKC iota on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Recombinant Human PKC iota Protein
Beta LifeScience
SKU/CAT #: BLK-00183P-100UG
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Description | Recombinant Human PKC iota Protein is expressed from Baculovirus-Insect Cells with His tag at the C-terminus.It contains Met10-Val596. |
Purity | > 95% as determined by Tris-Bis PAGE |
Accession | P41743 |
Target Symbol | PKC iota |
Species | Human |
Expression System | Baculovirus-Insect Cells |
Tag | C-His |
Expression Range | Met10-Val596 |
Mol. Weight | The protein has a predicted MW of 68.78 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result. |
Form | Liquid |
Formulation | Supplied as 0.22 um filtered solution in 50mM Tris, 100mM NaCl, 0.5mM GSH, 0.5mM PMSF, 10% glycerol (pH 7.4). |
Endotoxin | Less than 1EU per ug by the LAL method. |
Storage | Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping | Shipped with dry ice. |
Gene Background | PKClambda/iota belongs to the third group of the PKC family, atypical PKC (aPKC), together with PKCzeta based on its sequence divergence from conventional and novel PKCs observed not only in the N-terminal regulatory domain but also in the kinase domain. Although one of the most distinct features of aPKC is its single, unrepeated cysteine-rich domain, recent studies have revealed that the N-terminal regulatory domain has additional aPKC-specific structural motifs involved in various protein-protein interactions, which are important for the regulation and the subcellular targeting of aPKC. |