Interleukins and Receptors
5 products
Interleukins (ILs) are a group of cytokines that play key roles in immune system regulation and communication. They are involved in various immune responses, including inflammation, cell growth, differentiation, and immune cell activation. Interleukins are produced by different cell types, such as immune cells (e.g., T cells, B cells, macrophages) and non-immune cells (e.g., fibroblasts, endothelial cells), which interact with specific cell surface receptors to fulfill their functions.
Interleukin receptors are transmembrane proteins expressed on the surface of target cells. They are responsible for recognizing and binding specific interleukins, initiating intracellular signaling pathways, and regulating cellular responses. Receptor complexes usually consist of two or more subunits, including a ligand-binding subunit and a signaling subunit. Binding of interleukins to their receptors results in the activation of downstream signaling cascades, leading to changes in gene expression, cytokine production, cell proliferation, and immune cell activation.The binding affinity and specificity between interleukins and their receptors determine the biological response of target cells. Dysregulation or dysfunction of the interleukin signaling pathway can lead to various immune disorders, inflammatory diseases, and even cancer. Understanding the complex interplay between interleukins and their receptors is critical for deciphering immune system regulation, disease pathogenesis, and the development of targeted therapies. Researchers are actively studying signaling mechanisms and designing therapeutics that modulate interleukin signaling to treat immune-related diseases and improve patient outcomes.
We offer a wide selection of interleukins, including IL-1, IL-2, IL-6, IL-10, IL-12, IL-17 families and more, each with their unique functions and effects on the body. Our interleukins and receptors can be used as biological response modifiers to boost the immune system in cancer therapy, promoting the activation, regulation, and proliferation of immune cells to fight cancer. In addition, our Interleukin Receptor products are designed to specifically recognize and bind to their respective Interleukins, providing you with a powerful tool to study the signaling pathways and functions of Interleukins in the immune system and beyond.
Our interleukins and receptors are rigorously tested to achieve optimal performance, high purity and activity, ensuring reliable and reproducible results for your experiments. Inquire online or call us today to learn more about our products and services.
Features:
- High purity
- High biological activity
- Low in endotoxin (<10EU/mg)
- Low batch variation
