Biotinylated Cynomolgus GFRAL/GFR alpha-like Protein, Active
Beta LifeScience
SKU/CAT #: BLK-00993P-100UG

Biotinylated Cynomolgus GFRAL on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Biotinylated Cynomolgus GFRAL/GFR alpha-like Protein, Active
Beta LifeScience
SKU/CAT #: BLK-00993P-100UG
Collections: High-quality recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Description | Recombinant Biotinylated Cynomolgus GFRAL/GFR alpha-like Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Gln20-Glu351. |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Accession | XP_015304775.2 |
Target Symbol | GFRAL/GFR alpha-like |
Species | Cynomolgus |
Expression System | HEK293 |
Tag | N-His-Avi |
Expression Range | Gln20-Glu351 |
Mol. Weight | The protein has a predicted MW of 40.7 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result. |
Form | Liquid |
Formulation | Supplied as 0.22um filtered solution in 20mM PB, 400mM NaCl (pH 6.0). |
Endotoxin | Less than 1EU per ug by the LAL method. |
Activity | Immobilized Cynomolgus GDF15, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Cynomolgus GFRAL, His Tag with the EC50 of 101.8ng/ml determined by ELISA. Contact us for detailed testing images. |
Storage | Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping | Shipped with dry ice. |
Gene Background | GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. |