Biotinylated Cynomolgus Siglec-10 Protein
Beta LifeScience
SKU/CAT #: BLK-00197P-100UG

Biotinylated Cynomolgus Siglec-10 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Biotinylated Cynomolgus Siglec-10 Protein
Beta LifeScience
SKU/CAT #: BLK-00197P-100UG
Collections: High-quality recombinant proteins, Other recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Description | Recombinant Biotinylated Cynomolgus Siglec-10 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Thr17-Asn552. |
Purity | > 95% as determined by Tris-Bis PAGE |
Accession | A0A2K5WBX8 |
Target Symbol | Siglec-10 |
Species | Cynomolgus |
Expression System | HEK293 |
Tag | C-His-Avi |
Expression Range | Thr17-Asn552 |
Mol. Weight | The protein has a predicted MW of 61.71 kDa. Due to glycosylation, the protein migrates to 72-82 kDa based on Tris-Bis PAGE result. |
Form | Liquid |
Formulation | Supplied as 0.22 um filtered solution in 25mM MES, 150mM NaCl, 0.5M Arginine (pH 5.0). |
Endotoxin | Less than 1EU per ug by the LAL method. |
Storage | Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping | Shipped with dry ice. |
Gene Background | Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system. |