Biotinylated Human Siglec-5/CD170 Protein (Primary Amine Labeling)
Beta LifeScience
SKU/CAT #: BLK-01395P-100UG

Biotinylated Human Siglec-5 on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.
Biotinylated Human Siglec-5/CD170 Protein (Primary Amine Labeling)
Beta LifeScience
SKU/CAT #: BLK-01395P-100UG
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Description | Recombinant Biotinylated Human Siglec-5/CD170 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu17-Thr434. |
Purity | > 95% as determined by Tris-Bis PAGE |
Accession | O15389 |
Target Symbol | Siglec-5/CD170 |
Synonyms | CD170; CD33 antigen-like 2; CD33L2; OBBP2; Siglec5; SIGLEC5; OB-BP2 |
Species | Human |
Expression System | HEK293 |
Tag | C-hFc |
Expression Range | Glu17-Thr434 |
Mol. Weight | The protein has a predicted MW of 73.1 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on Tris-Bis PAGE result. |
Form | Lyophilized |
Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Endotoxin | Less than 1EU per ug by the LAL method. |
Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Shipping | Shipped at ambient temperature. |
Gene Background | Group B Streptococcus (GBS) causes invasive infections in human newborns. the GBS β-protein attenuates innate immune responses by binding to sialic acid-binding immunoglobulin-like lectin 5 (Siglec-5), an inhibitory receptor on phagocytes.the polymorphism could influence the risk of prematurity among human fetuses of mothers colonized with GBS. This first functionally proven example of a paired receptor system in the Siglec family has multiple implications for regulation of host immunity. |