Recombinant Human DNAM-1/CD226 Protein, Active
Beta LifeScience
SKU/CAT #: BLK-02281P-100UG
Human DNAM-1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Recombinant Human DNAM-1/CD226 Protein, Active
Beta LifeScience
SKU/CAT #: BLK-02281P-100UG
Collections: Car-nk targets proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Description | Recombinant Human DNAM-1/CD226 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu19-Asn247. |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Accession | Q15762 |
Target Symbol | DNAM-1/CD226 |
Synonyms | CD226 molecule; CD226; DNAM1; PTA1; TLiSA1 |
Species | Human |
Expression System | HEK293 |
Tag | C-hFc |
Expression Range | Glu19-Asn247 |
Mol. Weight | The protein has a predicted MW of 52.8 kDa. Due to glycosylation, the protein migrates to 70-100 kDa based on Tris-Bis PAGE result. |
Form | Lyophilized |
Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Endotoxin | Less than 1EU per ug by the LAL method. |
Activity | Immobilized Biotinylated Human CD155, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human DNAM-1, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA (QC Test). The affinity constant of 0.234 uM as determined in SPR assay (Biacore T200). Contact us for detailed testing images. |
Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Shipping | Shipped at ambient temperature. |
Gene Background | DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2. |