Recombinant Interleukin-2 (IL-2) Proteins

27 products

Background

Crystal structure of IL-2 as published in the Protein Data Bank (PDB: 1M47)

Interleukin-2 (IL-2), a cytokine, plays a vital role in the immune system. It is primarily produced by activated helper T cells and cytotoxic T cells but can also be found in other immune cells. IL-2 binds to the IL-2 receptor on the surface of T cells, triggering complex signaling pathways that promote the growth, proliferation, and differentiation of T cells, thereby strengthening the immune response. Its regulatory effect extends beyond T cells and includes other immune cells such as B cells and natural killer cells. The use of IL-2 has been explored in immunotherapy to enhance the immune system's resistance to diseases like cancer. However, excessive activation of IL-2 may be associated with autoimmune diseases. In summary, IL-2 plays an indispensable role in maintaining immune balance, fighting infections, and combating tumors, making it crucial for the normal functioning of the immune system.


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Featured Products

Cat. No. Species Product Description Host Structure Purity Activity Features
BLC-05337P Human Human IL-2 Protein, Active E.coli P60568 (21-153aa) > 95% ≥1×10^7 IU/mg SDS-PAGE, Cell Based Assay
BLC-05319P Human Human IL-2 Protein, Active Mammalian cell P60568 21-153aa (L80F & R81D & L85V & I86V & I92F) > 95% ED50: 0.5 ng/mL SDS-PAGE, Cell Based Assay
BLC-10775P Human Human IL-2 Protein (GST) E.coli P60568 (21-153aa) > 90% Testing in Progress SDS-PAGE
BLC-05416P Human Human IL-2 Protein, Active, GMP E.Coli P60568 (21-153aa) > 98% > 1.0 × 107 IU/mg SDS-PAGE, Cell Based Assay
BLC-03457P Human Human IL-2 Protein (His) E.coli P60568 (21-153aa) > 85% Testing in Progress SDS-PAGE
BLC-03039P Human Human IL-2 Protein (His) Yeast P60568 (21-153aa) > 90% Testing in Progress SDS-PAGE
BLC-05429P Human Human IL-2 Protein (His), Active Mammalian cell P60568 (21-153aa) > 95% ED50: 0.5 ng/mL SDS-PAGE, Cell Based Assay
Human Human IL-2 Protein, Active Mammalian cell P60568 (21-153aa) > 95% ≥ 1 x 107 IU/mg SDS-PAGE, Cell Based Assay
BL-1714NP Human Human IL-2 Protein E.coli P60568 (21-153aa) > 95% ≥1×107 IU/mg SDS-PAGE, Cell Based Assay, BLI
BL-2899NP Human Human IL-2 Superkine Protein (Mutant, C-6His) Mammalian cell P60568 21-153aa (L100F, R101D, L105V, I106V, I112F) > 95% ED50: 151.39 pg/mL SDS-PAGE, Cell Based Assay, BLI
BL-2730NP Human Biotinylated Human IL-2 Protein (C-6His-Avi) Mammalian cell P60568 (21-153aa) > 90% ED50: 0.2 ng/mL SDS-PAGE, Cell Based Assay, BLI, ELISA
BL-2127NP Human Human IL-2 Protein (C-6His) Mammalian cell P60568 (21-153aa) > 95% ≥1×107 IU/mg SDS-PAGE, Cell Based Assay, BLI
BL-2887NP Human Human IL-2 Protein (aldesleukin) E.coli P60568 (22-153aa) > 95% ED50: 90-270 pg/mL SDS-PAGE, Cell Based Assay, BLI
BLC-02916P Rhesus macaque Rhesus Macaque IL-2 Protein (His-SUMO&Myc) E.coli P68291 (21-154aa) > 90% Testing in Progress SDS-PAGE
BLPSN-2803 Canine Canine IL-2 Protein (147 Cys/Ser) E.coli Q29416 (21-155aa,147Cys/Ser) > 95% Binds rh-IL2Ra-Fc at b/t 0.3125-20 μg/mL SDS-PAGE, ELISA
BLC-06764P Llama Lama Glama IL-2 Protein (His) Yeast Q865X2 (21-154aa) > 90% Testing in Progress SDS-PAGE
BLC-06596P Llama Lama Glama IL-2 Protein (His) E.coli Q865X2 (21-154aa) > 90% Testing in Progress SDS-PAGE
BLC-00201P Golden hamster Mesocricetus Auratus IL-2 Protein (His&StrepII) E.coli B3VBJ5 (21-155aa) > 90% Testing in Progress SDS-PAGE
BLC-05311P Mouse Mouse IL-2 Protein, Active E.coli P04351 (21-169aa) > 95% ED50: < 0.5 ng/mL. SDS-PAGE, Cell Based Assay
BLPSN-2805 Mouse Mouse IL-2 Protein E.coli P04351 (21-169aa) > 92% ED50: 6-30 ng/mL. SDS-PAGE, Cell Based Assay, ELISA
BLC-11012P Rabbit Rabbit IL-2 Protein (His) Yeast O77620 ( 21-153aa) > 85% Testing in Progress SDS-PAGE
BLC-04118P Rabbit Rabbit IL-2 Protein (His) E.coli O77620 ( 21-153aa) > 90% Testing in Progress SDS-PAGE
BLPSN-2806 Rat Rat IL-2 Protein E.coli P17108 (21-155aa) > 95% ED50: 0.5-3 ng/mL SDS-PAGE, Cell Based Assay, ELISA

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