Recombinant Human VEGFB Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-4771
Recombinant Human VEGFB Protein (Fc Tag)
Beta LifeScience
SKU/CAT #: BLPSN-4771
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | Fc |
Host Species | Human |
Accession | NP_003368.1 |
Synonym | VEGFL, VRF |
Background | Vascular endothelial growth factor-B (VEGF-B) is closely related to VEGF-A, an effector of blood vessel growth during development and disease and a strong candidate for angiogenic therapies. In details, VEGFB can positively prevent the Ang II-induced rising in the size of cardiomyocyte as well as reduce Ang II-induced mRNA and protein levels of beta-MHC (beta-myosin heavy chain), BNP (brain natriuretic peptide), and ANP (atrial natriuretic peptide). Moreover, VEGFB can regulate the decline of the Ang II-induced rising in Ca2+ . |
Description | A DNA sequence encoding the human VEGFB (NP_003368.1) (Pro22-Ala207) was expressed with the Fc region of human IgG1 at the N-terminus. |
Source | HEK293 |
Predicted N Terminal | Glu |
AA Sequence | Pro22-Ala207 |
Molecular Weight | The recombinant human VEGFB consists 446 a.a. and predicts a molecular mass of 47.8 kDa. |
Purity | >(75.2+22)% as determined by SDS-PAGE. |
Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
Bioactivity | Measured by its binding ability in a functional ELISA.Immobilized human S4-Fc3L3-VEGFB at 10 ug/ml (100 uL/well) can bind biotinylated human NRP1-Fc , The EC50 of biotinylated human NRP1-Fc is 0.03-0.07ug/mL. |
Formulation | Lyophilized from sterile PBS, pH 7.4.. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |