Recombinant Human UBE2D1 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-4712
Recombinant Human UBE2D1 Protein (His Tag)
Beta LifeScience
SKU/CAT #: BLPSN-4712
Collections: Other recombinant proteins, Recombinant proteins
Our products are highly customizable to meet your specific needs. You can choose options such as endotoxin removal, liquid or lyophilized forms, preferred tags, and the desired functional sequence range for proteins. Submitting a written inquiry expedites the quoting process.
Product Overview
Tag | His |
Host Species | Human |
Accession | P51668 |
Synonym | E2(17)KB1, SFT, UBC4/5, UBCH5, UBCH5A |
Background | Ubiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis, as previously published for SFT. Moreover, a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant KRAS to kill cancer cells. |
Description | A DNA sequence encoding the human UBE2D1 (P51668) (Ala 2-Met 147) was expressed, with a His tag at the N-terminus. |
Source | E.coli |
Predicted N Terminal | Met |
AA Sequence | Ala 2-Met 147 |
Molecular Weight | The recombinant human UBE2D1 consisting of 161 a.a. and has a calculated molecular mass of 18.3 kDa. It migrates as an approximately16 kDa band in SDS-PAGE under reducing conditions. |
Purity | >90% as determined by SDS-PAGE |
Endotoxin | Please contact us for more information. |
Bioactivity | Please contact us for detailed information |
Formulation | Lyophilized from sterile 25mM Tris, 100mM NaCl, 20% glycerol, 0.05% Tween. |
Stability | The recombinant proteins are stable for up to 1 year from date of receipt at -70°C. |
Usage | For Research Use Only |
Storage | Store the protein under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |